HCID 57468723, compound → HCID 24760664, compound

HRID 1989544Notes

Reaction equation

HRID 1989544 reaction equation
[OH:1][NH:2][C:3](=[NH:14])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([S:10](=[O:13])(=[O:12])[NH2:11])[CH:5]=1.[CH3:15][C:16]1[N:21]=[C:20]([C:22](O)=O)[CH:19]=[C:18]([C:25]2[CH:30]=[CH:29][C:28]([C:31]([F:34])([F:33])[F:32])=[CH:27][CH:26]=2)[CH:17]=1>>[CH3:22][C:20]1[N:21]=[C:16]([C:15]2[O:1][N:2]=[C:3]([C:4]3[CH:5]=[C:6]([S:10]([NH2:11])(=[O:12])=[O:13])[CH:7]=[CH:8][CH:9]=3)[N:14]=2)[CH:17]=[C:18]([C:25]2[CH:26]=[CH:27][C:28]([C:31]([F:34])([F:33])[F:32])=[CH:29][CH:30]=2)[CH:19]=1

Participants

3

Reactant 2

HCID 57468723HCID 57468723, compoundHCID 178513322HCID 178513322, compound

Product 1

HCID 24760664HCID 24760664, compound

Procedure

The title compound was prepared from N-hydroxy-3-sulfamoyl-benzamidine [CAS-No. 9000-88-7] (0.115 g, 0.53 mmol) and 6-methyl-4-(4-trifluoromethyl-phenyl)-pyridine-2-carboxylic acid (example D.11) (0.10 g, 0.36 mmol) according to the general procedure V. Obtained as an off-white solid (0.080 g, 49%). MS (ISP) 461.0 [(M+H)+]; mp 277° C.

Sources & evidence

ORD record
ord-e68a59465a8b4efe9f982a1fe2cc8d38
Source dataset
uspto-grants-2010_01
Patent number
US07642264B2

Reaction notes

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