HCID 57468838, compound → HCID 60209460, compound

HRID 1989565Notes

Reaction equation

HRID 1989565 reaction equation
[CH3:1][C:2]1[N:7]=[C:6]([C:8]2[CH:9]=[C:10](B(O)O)[CH:11]=[CH:12][CH:13]=2)[CH:5]=[C:4]([C:17]2[CH:22]=[CH:21][C:20]([C:23]([F:26])([F:25])[F:24])=[CH:19][CH:18]=2)[CH:3]=1.Br[C:28]1[CH:29]=[C:30]([S:34]([NH:37][O:38][CH3:39])(=[O:36])=[O:35])[CH:31]=[CH:32][CH:33]=1>>[CH3:39][O:38][NH:37][S:34]([C:30]1[CH:31]=[C:32]([C:10]2[CH:11]=[CH:12][CH:13]=[C:8]([C:6]3[CH:5]=[C:4]([C:17]4[CH:22]=[CH:21][C:20]([C:23]([F:25])([F:24])[F:26])=[CH:19][CH:18]=4)[CH:3]=[C:2]([CH3:1])[N:7]=3)[CH:9]=2)[CH:33]=[CH:28][CH:29]=1)(=[O:36])=[O:35]

Participants

3

Reactant 2

HCID 57468838HCID 57468838, compoundHCID 602093413-[6-Methyl-4-(4-trifluoromethyl-phenyl)pyridin-2-yl]-benzeneboronic acid

Product 1

HCID 60209460HCID 60209460, compound

Procedure

The title compound was prepared from 3-[6-methyl-4-(4-trifluoromethyl-phenyl)pyridin-2-yl]-benzeneboronic acid (example G.9) (0.20 g, 0.56 mmol) and 3-bromo-N-methoxy-benzenesulfonamide (example H.3) (0.149 g, 0.56 mmol) according to the general procedure VI. Obtained as a white solid (0.120 g, 43%). MS (ISP) 499.2 [(M+H)+]; mp 181° C.

Sources & evidence

ORD record
ord-f817d885f53f43e9933a3f9283935979
Source dataset
uspto-grants-2010_01
Patent number
US07642264B2

Reaction notes

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