HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(tert-Butylaminosulphonyl)benzeneboronic acid → N-tert-Butyl-3-[6-methyl-4-(4-trifluoromethyl-phenyl)-[2,3']bipyridinyl-5'-yl]-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(tert-Butylaminosulphonyl)benzeneboronic acid | HCID 44119538 | — |
| Reactant | 5'-Bromo-6-methyl-4-(4-trifluoromethylphenyl)-[2,3']bipyridinyl | HCID 68692484 | — |
| Product | N-tert-Butyl-3-[6-methyl-4-(4-trifluoromethyl-phenyl)-[2,3']bipyridinyl-5'-yl]-benzenesulfonamide | HCID 24760815 | — |
Reaction Steps
The title compound was prepared from 5′-bromo-6-methyl-4-(4-trifluoromethylphenyl)-[2,3′]bipyridinyl (example E.24) (0.200 g, 0.5 mmol) and commercially available 3-(tert-butylsulfamoyl)-benzeneboronic acid (0.157 g, 0.6 mmol) according to the general procedure VI. Obtained as an off-white solid (0.182 g, 68%). MS (ISP) 526.3 [(M+H)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07642264B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-4a47146d6d6444f0956cc98d2180dcd3 |
| Source note | uspto-grants-2010_01 |