HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(tert-Butylaminosulphonyl)benzeneboronic acid → N-tert-Butyl-3-[4'-methyl-6'-(4-trifluoromethyl-phenyl)-[2,2']bipyridinyl-6-yl]-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(tert-Butylaminosulphonyl)benzeneboronic acid | HCID 44119538 | — |
| Reactant | HCID 86615446 | HCID 86615446 | — |
| Product | N-tert-Butyl-3-[4'-methyl-6'-(4-trifluoromethyl-phenyl)-[2,2']bipyridinyl-6-yl]-benzenesulfonamide | HCID 68692928 | — |
Reaction Steps
The title compound was prepared from 6′-bromo-4-methyl-6-(4-trifluoromethylphenyl)-[2,2′]bipyridinyl (example E.96) (0.393 g, 1.0 mmol) and commercially available 3-(tert-butylsulfamoyl)-benzeneboronic acid (0.283 g, 1.1 mmol) according to the general procedure VI. Obtained as a white solid (0.500 g, 95%). MS (ISP) 526.3 [(M+H)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07642264B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-3a414c63a53548ba912aea0e8cb6cc3d |
| Source note | uspto-grants-2010_01 |