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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 198962Generated: November 1, 2026

Methyl 2-chloropyrimidine-5-carboxylate → 2-{4-Chloro-3-[2-(2-chloro-pyridin-4-yl)-3,3,3-trifluoro-2-hydroxy-1-methyl-propyl]-phenoxy}-pyrimidine-5-carboxylic acid methyl ester

https://huagongshe.com/reaction/198962

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-chloropyrimidine-5-carboxylateHCID 12627752—
Reactant4-Chloro-3-[2-(2-chloro-pyridin-4-yl)-3,3,3-trifluoro-2-hydroxy-1-methyl-propyl]-phenolHCID 25254603—
Product2-{4-Chloro-3-[2-(2-chloro-pyridin-4-yl)-3,3,3-trifluoro-2-hydroxy-1-methyl-propyl]-phenoxy}-pyrimidine-5-carboxylic acid methyl esterHCID 72310574—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-005a5c6d9a43488bbc0012ede84a1ecc
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)