HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(Methylthio)benzeneboronic acid → 6-Methyl-6'-(3-methylsulfanyl-phenyl)-4-(4-trifluoromethyl-phenyl)-[2,2']bipyridinyl
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(Methylthio)benzeneboronic acid | HCID 2734383 | — |
| Reactant | 6'-Bromo-6-methyl-4-(4-trifluoromethylphenyl)-[2,2']bipyridinyl | HCID 86615440 | — |
| Product | 6-Methyl-6'-(3-methylsulfanyl-phenyl)-4-(4-trifluoromethyl-phenyl)-[2,2']bipyridinyl | HCID 24760661 | — |
Reaction Steps
The title compound was prepared from 6′-bromo-6-methyl-4-(4-trifluoromethylphenyl)-[2,2′]bipyridinyl (example E.26) (0.39 g, 1.1 mmol) and commercially available 3-(methylthio)phenylboronic acid (0.183 g, 1.1 mmol) according to the general procedure VI. Obtained as a white solid (0.150 g, 31%). MS (ISP) 437.1 [(M+H)+]; mp 144° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07642264B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-d5078445f5d34b95b2b2b737f7ac9b2e |
| Source note | uspto-grants-2010_01 |