HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Azetidin-1-ylcarbonyl)-5-bromopyridine → 3-{[6-(azetidin-1-ylcarbonyl)pyridin-3-yl]oxy}-N-(1-ethyl-1H-pyrazol-3-yl)-5-{[(1S)-1-methyl-2-(methyloxy)ethyl]oxy}benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Azetidin-1-ylcarbonyl)-5-bromopyridine | HCID 53629617 | — |
| Reactant | N-(1-Ethyl-1H-pyrazol-3-yl)-3-hydroxy-5-{[(1S)-1-methyl-2-(methyloxy)ethyl]oxy}benzamide | HCID 59127176 | — |
| Product | 3-{[6-(azetidin-1-ylcarbonyl)pyridin-3-yl]oxy}-N-(1-ethyl-1H-pyrazol-3-yl)-5-{[(1S)-1-methyl-2-(methyloxy)ethyl]oxy}benzamide | HCID 16039686 | — |
Reaction Steps
The preparation of N-(1-ethyl-1H-pyrazol-3-yl)-3-hydroxy-5-{[(1S)-1-methyl-2-(methyloxy)ethyl]oxy}benzamide and 2-(azetidin-1-ylcarbonyl)-5-bromopyridine was described earlier.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07642263B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-2711c43a4fa44065a3c9a3ad2d9926e8 |
| Source note | uspto-grants-2010_01 |