HuagongsheHuagongshe Chemistry Print Report · For research reference only
methyl 3-(benzyloxy)-5-[(1R)-2-methoxy-1-methylethoxy]benzoate → Methyl 3-hydroxy-5-{[(1R)-1-methyl-2-(methyloxy)ethyl]oxy}benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | methyl 3-(benzyloxy)-5-[(1R)-2-methoxy-1-methylethoxy]benzoate | HCID 59127090 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | Methyl 3-hydroxy-5-{[(1R)-1-methyl-2-(methyloxy)ethyl]oxy}benzoate | HCID 59127121 | — |
Reaction Steps
A solution of methyl 3-{[(1R)-1-methyl-2-(methyloxy)ethyl]oxy}-5-[(phenylmethyl)oxy]benzoate in THF (5 mL) and ethanol (5 mL), containing 10% palladium on carbon, was stirred under an atmosphere of hydrogen for 16 hours. The palladium on carbon was removed by filtration and the filtrate evaporated under reduced pressure to give the desired material as a clear gum (723 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07642263B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-ef3a6c8668e44a66be22beee8a7d0027 |
| Source note | uspto-grants-2010_01 |