HCID 68522041, compound → HCID 86612410, compound

HRID 1990084Notes

Reaction equation

HRID 1990084 reaction equation
COC(C1SC([N:22]=[N+:23]=[N-:24])=C(C#N)C=1C1C=CC=CC=1C(C)(C)C)=O.[CH2:25]([O:27][C:28]([C:30]1[S:31][C:32](S(C)(=O)=O)=[C:33]([C:42]#[N:43])[C:34]=1[C:35]1[CH:40]=[CH:39][C:38]([I:41])=[CH:37][CH:36]=1)=[O:29])[CH3:26]>>[CH2:25]([O:27][C:28]([C:30]1[S:31][C:32]([N:22]=[N+:23]=[N-:24])=[C:33]([C:42]#[N:43])[C:34]=1[C:35]1[CH:40]=[CH:39][C:38]([I:41])=[CH:37][CH:36]=1)=[O:29])[CH3:26]

Participants

3

Reactant 2

HCID 68522041HCID 68522041, compoundHCID 86612409HCID 86612409, compound

Product 1

HCID 86612410HCID 86612410, compound

Procedure

Using a method substantially in accordance with the method of example 5-azido-3-(tert-butyl-phenyl)-4-cyano-thiophene-2-carboxylic acid methyl ester starting with the compound 3-(4-iodophenyl)-4-cyano-5-methanesulfonyl-thiophene-2-carboxylic acid ethyl ester gives the title compound.

Sources & evidence

ORD record
ord-961ec4031e5a487681f56ab476292091
Source dataset
uspto-grants-2010_01
Patent number
US07642361B2

Reaction notes

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