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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1990228Generated: October 30, 2026

2-(Azetidin-1-ylcarbonyl)-5-bromopyridine → 3-{[6-(azetidin-1-ylcarbonyl)pyridin-3-yl]oxy}-5-{[(1S)-1-methyl-2-(methyloxy)ethyl]oxy}benzoic acid

https://huagongshe.com/reaction/1990228

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Azetidin-1-ylcarbonyl)-5-bromopyridineHCID 53629617—
Reactantmethyl 3-hydroxy-5-[(1S)-2-methoxy-1-methylethoxy]benzoateHCID 59127146—
Product3-{[6-(azetidin-1-ylcarbonyl)pyridin-3-yl]oxy}-5-{[(1S)-1-methyl-2-(methyloxy)ethyl]oxy}benzoic acidHCID 53629668—

Reaction Steps

3-{[6-(Azetidin-1-ylcarbonyl)pyridin-3-yl]oxy}-5-{[(1S)-1-methyl-2-(methyloxy)ethyl]oxy}benzoic acid was prepared in an analogous fashion from 2-(azetidin-1-ylcarbonyl)-5-bromopyridine and methyl 3-hydroxy-5-[(1S)-2-methoxy-(1-methylethyl)oxy]benzoate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07642259B2
Source datasetuspto-grants-2010_01
ORD IDord-cf40b7679f6348e0b163fbb53c0573a4
Source noteuspto-grants-2010_01