tert-Butyl 3-amino-1H-pyrazole-1-carboxylate → 3-(3-Benzyloxy-5-isopropoxy-benzoylamino)-pyrazole-1-carboxylic acid tert-butyl ester

HRID 1990229Notes

Reaction equation

HRID 1990229 reaction equation
[CH3:1][CH:2]([O:4][C:5]1[CH:6]=[C:7]([CH:11]=[C:12]([O:14][CH2:15][C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[CH:13]=1)[C:8]([OH:10])=O)[CH3:3].[NH2:22][C:23]1[CH:27]=[CH:26][N:25]([C:28]([O:30][C:31]([CH3:34])([CH3:33])[CH3:32])=[O:29])[N:24]=1>>[CH3:3][CH:2]([O:4][C:5]1[CH:6]=[C:7]([C:8]([NH:22][C:23]2[CH:27]=[CH:26][N:25]([C:28]([O:30][C:31]([CH3:34])([CH3:33])[CH3:32])=[O:29])[N:24]=2)=[O:10])[CH:11]=[C:12]([O:14][CH2:15][C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[CH:13]=1)[CH3:1]

Participants

3

Reactant 2

HCID 51358380tert-Butyl 3-amino-1H-pyrazole-1-carboxylateHCID 534011033-Benzyloxy-5-isopropoxybenzoic acid

Product 1

HCID 574692013-(3-Benzyloxy-5-isopropoxy-benzoylamino)-pyrazole-1-carboxylic acid tert-butyl ester

Procedure

The preparations of 3-[(1-methylethyl)oxy]-5-[(phenylmethyl)oxy]benzoic acid and 1,1-dimethylethyl 3-amino-1H-pyrazole-1-carboxylate were described earlier.

Sources & evidence

ORD record
ord-942c39d213cb414d8f61f192d28d43ae
Source dataset
uspto-grants-2010_01
Patent number
US07642259B2

Reaction notes

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