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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1990265Generated: October 29, 2026

2-(Azetidin-1-ylcarbonyl)-5-bromopyridine → 3-{[6-(Azetidin-1-ylcarbonyl)pyridin-3-yl]oxy}-5-{[(1S)-2-hydroxy-1-methylethyl]oxy}benzoic acid

https://huagongshe.com/reaction/1990265

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Azetidin-1-ylcarbonyl)-5-bromopyridineHCID 53629617—
Reactantmethyl 3-hydroxy-5-[(1S)-2-hydroxy-1-methylethoxy]benzoateHCID 59127187—
Product3-{[6-(Azetidin-1-ylcarbonyl)pyridin-3-yl]oxy}-5-{[(1S)-2-hydroxy-1-methylethyl]oxy}benzoic acidHCID 59127161—

Reaction Steps

The preparations of methyl 3-hydroxy-5-[(1S)-2-hydroxy-1-methylethoxy]benzoate and 2-(azetidin-1-ylcarbonyl)-5-bromopyridine were described earlier.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07642259B2
Source datasetuspto-grants-2010_01
ORD IDord-37990e015d8641249e60113720cea7bc
Source noteuspto-grants-2010_01