Dimethyl Sulfoxide → Methyl 2-fluoro-4-(4-thiomorpholinyl)benzoate

HRID 199060Notes

Reaction equation

HRID 199060 reaction equation
[C:23](=[O:24])([O-:25])[O-:26].[CH2:17]1[CH2:18][S:19][CH2:20][CH2:21][NH:22]1.[CH3:1][S:2](=[O:3])[CH3:4].[F:5][c:6]1[c:7]([C:8](=[O:9])[O:10][CH3:11])[cH:12][cH:13][c:14]([F:16])[cH:15]1.[K+:27].[K+:28].[OH2:29]>>[F:5][c:6]1[c:7]([C:8](=[O:9])[O:10][CH3:11])[cH:12][cH:13][c:14]([N:22]2[CH2:17][CH2:18][S:19][CH2:20][CH2:21]2)[cH:15]1

Participants

7

Reactant 6

HCID 679Dimethyl SulfoxideHCID 813Potassium Cation2×HCID 962WaterHCID 19660Carbonate IonHCID 67164ThiomorpholineHCID 2782897Methyl 2,4-Difluorobenzoate

Product 1

HCID 23024292Methyl 2-fluoro-4-(4-thiomorpholinyl)benzoate

Sources & evidence

ORD record
ord-1f08d63402184657b2df6f667321b3d8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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