HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromoethanol → 3-(2-Hydroxyethoxy)-4-(1-methylethoxy)benzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromoethanol | HCID 10898 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 94283-73-5 | HCID 15453521 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 3-(2-Hydroxyethoxy)-4-(1-methylethoxy)benzaldehyde | HCID 22039918 | — |
Reaction Steps
The title compound was prepared analogously to intermediate 2 (4-methoxy-3-propoxy-benzaldehyde) by reaction of 3-hydroxy-4-isopropoxy-benzaldehyde ([CAS RN 94283-73-5], F. R. Hewgill, M. C. Pass Australian J. Chem. 1985, 38, 537-554) with 2-bromo-ethanol in DMF using K2CO3 as base. MS (ISP): 224.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07645753B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-55407e49112142f9885f790fd1c9a258 |
| Source note | uspto-grants-2010_01 |