HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1990849Generated: October 29, 2026
(3-Ethoxy-5-isobutoxy-phenyl)-methanol → 3-Ethoxy-5-isobutoxy-benzaldehyde
https://huagongshe.com/reaction/1990849
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | (3-Ethoxy-5-isobutoxy-phenyl)-methanol | HCID 68694893 | — |
| Catalyst | Manganese dioxide | HCID 14801 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 3-Ethoxy-5-isobutoxy-benzaldehyde | HCID 58706326 | 100.8% |
Reaction Steps
To a solution of (3-ethoxy-5-isobutoxy-phenyl)-methanol (0.28 g, 1.25 mmol, 1.0 equiv) in DMF (20 mL) was added activated MnO2 (1.09 g, 12.48 mmol, 10.0 equiv). The reaction mixture was heated to 60° C. for 2 h, filtered through Hyflo Super Cel and concentrated by evaporation under reduced pressure yielding 0.28 g (99% yield) of the title compound. MS (ISP): 223.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07645753B2 |
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| Source dataset | uspto-grants-2010_01 |
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| ORD ID | ord-b4013a8a1e584b3f9476883d7a452734 |
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| Source note | uspto-grants-2010_01 |
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