2-Amino-4,6-dichloropyrimidine → 4-(7-bromo-3-methyl-3,4-dihydroisoquinolin-2(1H)-yl)-6-chloropyrimidin-2-amine

HRID 199089Notes

Reaction equation

HRID 199089 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:10]([cH:11]1)[CH2:9][NH:8][CH:7]([CH3:12])[CH2:6]2.[NH2:13][c:14]1[n:15][c:16]([Cl:21])[cH:17][c:18]([Cl:20])[n:19]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:10]([cH:11]1)[CH2:9][N:8]([c:18]1[cH:17][c:16]([Cl:21])[n:15][c:14]([NH2:13])[n:19]1)[CH:7]([CH3:12])[CH2:6]2

Participants

3

Reactant 2

HCID 655222-Amino-4,6-dichloropyrimidineHCID 444054957-Bromo-3-methyl-1,2,3,4-tetrahydroisoquinoline

Product 1

HCID 594023614-(7-bromo-3-methyl-3,4-dihydroisoquinolin-2(1H)-yl)-6-chloropyrimidin-2-amine

Sources & evidence

ORD record
ord-5cbfcabd67f74adba4b06516fe7c1d3a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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