HCID 68695975, compound → HCID 68699368, compound

HRID 1990904Notes

Reaction equation

HRID 1990904 reaction equation
[O:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[NH:10][CH:11]1[CH2:16][CH2:15][N:14]([CH2:17][C:18]2[N:19]=[C:20]([C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[NH:21][C:22]=2[CH3:23])[CH2:13][CH2:12]1.C(C1NC(C2C=C([NH:43][C:44](=[O:46])[CH3:45])C=CC=2)=NC=1C)=O>>[O:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[NH:10][CH:11]1[CH2:16][CH2:15][N:14]([CH2:17][C:18]2[N:19]=[C:20]([C:24]3[CH:29]=[C:28]([NH:43][C:44](=[O:46])[CH3:45])[CH:27]=[CH:26][CH:25]=3)[NH:21][C:22]=2[CH3:23])[CH2:13][CH2:12]1

Participants

3

Reactant 2

HCID 68695975HCID 68695975, compoundHCID 178474135HCID 178474135, compound

Product 1

HCID 68699368HCID 68699368, compound

Procedure

The title compound was prepared according to the procedure described for the synthesis of example 325 (benzooxazol-2-yl-[1-(5-methyl-2-phenyl-1H-imidazol-4-ylmethyl)-piperidin-4-yl]-amine) using N-[3-(5-formyl-4-methyl-1H-imidazol-2-yl)-phenyl]-acetamide instead of 5-methyl-2-phenyl-3H-imidazole-4-carbaldehyde. MS (ESI): 445.3 [M+H]+.

Sources & evidence

ORD record
ord-25db86cb694143458c26ad582e0c53e6
Source dataset
uspto-grants-2010_01
Patent number
US07645753B2

Reaction notes

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