2-[(Benzenesulfonyl)methyl]-4-bromo-1-nitrobenzene → 4-Bromo-2-[(phenylsulfonyl)methyl]benzenamine

Participants

Reaction Steps

This compound was prepared by catalytic hydrogenation of 5-bromo-2-nitrobenzyl phenyl sulfone (0.23 g, 0.64 mmol) in the presence of Raney nickel and hydrogen (45 psi) in ethyl acetate (30 ml) for 1 hour. The reaction mixture is filtered through celite and concentrated in vacuo to give the title compound as a light brown solid (0.21 g, 99%). Mp: 140-141° C. MS (ES+): 326 (M+H).

Provenance & Evidence