反应详情

Pd/C (5%, 0.05 g) was added to a mixture of 5-hydroxy-adamantan-2-one oxime (1 g, 5.5 mmol) in EtOH in a Parr hydrogenation bottle. The hydrogenation reaction was performed in a Parr hydrogenation instrument with 55 Psi pressure of hydrogen at room temperature for 72 hours. The mixture was filtered through celite and concentrated under vacuum to dryness to give 4-amino-adamantan-1-ol (0.82 g, 89%).

1. customThe hydrogenation reaction
2. filtrationThe mixture was filtered through celite
3. concentrationconcentrated under vacuum to dryness