Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Chloroform | HCID 6212 | — |
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | 3-Methoxyphenol | HCID 9007 | — |
| Reactant | Sulfuryl chloride | HCID 24648 | — |
| Product | HCID 58683723 | HCID 58683723 | 39% |
Reaction Steps
3-Methoxyphenol (14.9 g, 120.0 mmol) was dissolved in 60 ml chloroform. At 0° C. 17.12 g (126.0 mmol) sulfurylchloride were added dropwise over 1 hour. After 2 hours stirring at 0° C. 100 ml water and 50 ml DCM were added. The organic layer was separated and washed with water and saturated sodium chloride solution. The title compound was purified by chromatography (SiO2, ethyl acetate/c-hexane 2/8) and was isolated as a yellow liquid (7.50 g, 39%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07645760B2 |
|---|
| Source dataset | uspto-grants-2010_01 |
|---|
| ORD ID | ord-3a58933bea534b41bc1a62e7fe2cbfff |
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| Source note | uspto-grants-2010_01 |
|---|
