HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenethyl bromide → HCID 68608251, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenethyl bromide | HCID 7666 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 59128696 | HCID 59128696 | — |
| Catalyst | Tetrabutylammonium Iodide | HCID 67553 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 68608251 | HCID 68608251 | 50% |
Reaction Steps
According to the general procedure using: 27 (60 mg, 0.174 mmol), (2-bromo-ethyl)-benzene (143 μL, 1.05 mmol), K2CO3 (241 mg, 1.74 mmol) and n-Bu4NI (6.4 mg, 17 μmol) in acetone (4.0 mL) were heated at reflux overnight. Standard workup and purification by PTLC using AcOEt:hexane=6:4 (v/v) as eluent gave 28r as a clear oil (39 mg, 50%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07645769B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-0dfdeaed06a948c4900f1240529a398d |
| Source note | uspto-grants-2010_01 |