Ethyl 4-chlorosulfonyl-2-methylphenoxyacetate → (4-Chlorosulfonyl-5,6,7,8-tetrahydro-naphthalen-1-yloxy)-acetic acid ethyl ester

HRID 1991170Notes

Reaction equation

HRID 1991170 reaction equation
[CH2:1]([O:3][C:4](=[O:18])[CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([S:13]([Cl:16])(=[O:15])=[O:14])=[CH:9][C:8]=1[CH3:17])[CH3:2].C(OC(=O)CO[C:25]1[C:34]2CCCCC=2C=C[CH:26]=1)C>>[CH2:1]([O:3][C:4](=[O:18])[CH2:5][O:6][C:7]1[C:8]2[CH2:17][CH2:34][CH2:25][CH2:26][C:9]=2[C:10]([S:13]([Cl:16])(=[O:14])=[O:15])=[CH:11][CH:12]=1)[CH3:2]

Participants

3

Reactant 2

HCID 11415129Ethyl 4-chlorosulfonyl-2-methylphenoxyacetateHCID 23224048(5,6,7,8-Tetrahydro-naphthalen-1-yloxy)-acetic acid ethyl ester

Product 1

HCID 20768129(4-Chlorosulfonyl-5,6,7,8-tetrahydro-naphthalen-1-yloxy)-acetic acid ethyl ester

Procedure

The title compound was prepared according to the method described for preparing compound 10.2, using compound 22.1 as the starting material. 1H NMR (400 MHz) (CDCl3) δ 7.93 (1H, d, J=8.9 Hz); 6.62 (1H, d, J=9.0 Hz); 4.73 (2H, s); 4.29 (2H, q, J=7.1 Hz); 3.27-3.24 (2H, m); 2.81-2.78 (2H, m); 1.85-1.82 (4H, m); 1.32 (3H, t, J=7.2 Hz).

Sources & evidence

ORD record
ord-b95aafbe90a44cb2b4720006f649fef2
Source dataset
uspto-grants-2010_01
Patent number
US07645779B2

Reaction notes

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