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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1991179Generated: October 31, 2026

4-[[2-Chloro-4-[(4-trifluoromethylphenoxy)methyl]phenyl]sulfanyl]-2-methylphenoxy-acetic acid ethyl ester → {4-[2-Chloro-4-(4-trifluoromethyl-phenoxymethyl)-phenylsulfanyl]-2,5-dimethyl-phenoxy}-acetic acid ethyl ester

https://huagongshe.com/reaction/1991179

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[[2-Chloro-4-[(4-trifluoromethylphenoxy)methyl]phenyl]sulfanyl]-2-methylphenoxy-acetic acid ethyl esterHCID 20768114—
Reactant[4-(2-Chloro-4-hydroxymethyl-phenylsulfanyl)-2,5-dimethyl-phenoxy]-acetic acid ethyl esterHCID 20768117—
Product{4-[2-Chloro-4-(4-trifluoromethyl-phenoxymethyl)-phenylsulfanyl]-2,5-dimethyl-phenoxy}-acetic acid ethyl esterHCID 20768113—

Reaction Steps

The title compound was prepared according to the method described for preparing compound 10.6, using compound 24.2 as the starting material. 1H NMR (400 MHz) (CDCl3) δ 7.54 (2H, d, J=8.8 Hz); 7.42 (1H, d, J=1.6 Hz); 7.34 (1H, s); 7.06 (1H, dd, J=1.8, 8.2 Hz); 6.99 (2H, d, J=8.7 Hz); 6.67 (1H, s); 6.51 (1H, d, J=8.2 Hz); 4.99 (2H, s); 4.68 (2H, s); 4.30 (2H, q, J=7.1 Hz); 2.31 (3H, s); 2.25 (3H, s); 1.32 (3H, t, J=7.2 Hz).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07645779B2
Source datasetuspto-grants-2010_01
ORD IDord-9e0305be8f854c58ae2549183cb731b1
Source noteuspto-grants-2010_01