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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1991219Generated: October 31, 2026

Benzimidazole → 2-(1H-Benzimidazol-1-yl)-N-(4-tert-butylphenyl)acetamide

https://huagongshe.com/reaction/1991219

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzimidazoleHCID 5798—
ReactantBromoacetyl bromideHCID 61147—
Reactant4-Tert-ButylanilineHCID 69861—
Reactant2-Bromo-N-(4-(tert-butyl)phenyl)acetamideHCID 60651186—
Product2-(1H-Benzimidazol-1-yl)-N-(4-tert-butylphenyl)acetamideHCID 26217892—

Reaction Steps

The title compound was synthesised according to the procedure described in Example 94 from 1H-benzoimidazole and 2-bromo-N-(4-tert-butyl-phenyl)-acetamide. The latter was synthesized from bromoacetyl bromide and 4-tert-butyl-aniline. Calculated for C19H21N3O m/z: 307.3, found 308.4 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07645784B2
Source datasetuspto-grants-2010_01
ORD IDord-7fc709c55cb34853b75d6f37d37863b8
Source noteuspto-grants-2010_01