Methylamine → HCID 10125855, compound

Participants

Reaction Steps

The methyl(5R)-3-(2,3-dihydro-3-isopropyl-2-oxo-6-benzothiazolyl)-2-oxo -5-oxazolidinecarboxylate (EXAMPLE 31, Step 3, 2.89 g, 8.59 mmol) is treated with 2N methylamine in MeOH (8.2 mL), and the mixture is stirred at ambient temperature for 45 mins and then filtered to give the title compound, mp 172-173.5° C.; MS (ESI+) for C15H17N3O4S m/z 336 (M+H)+; [α]25D−43 (c 0.98, DMSO).

Provenance & Evidence