Chloroacetyl chloride → HCID 59128931, compound

HRID 1991385Notes

Reaction equation

[C:1]([C:5]1[CH:22]=[CH:21][CH:20]=[CH:19][C:6]=1[O:7][C:8]1[C:13]([NH:14][C:15](=[S:18])[NH:16][NH2:17])=[CH:12][CH:11]=[CH:10][N:9]=1)([CH3:4])([CH3:3])[CH3:2].[Cl:23][CH2:24][C:25](Cl)=O>>[C:1]([C:5]1[CH:22]=[CH:21][CH:20]=[CH:19][C:6]=1[O:7][C:8]1[C:13]([NH:14][C:15]2[S:18][C:25]([CH2:24][Cl:23])=[N:17][N:16]=2)=[CH:12][CH:11]=[CH:10][N:9]=1)([CH3:4])([CH3:2])[CH3:3]

Participants

Reactant 2

HCID 6577Chloroacetyl chloride

HCID 59128834HCID 59128834, compound

Product 1

HCID 59128931HCID 59128931, compound

Procedure

Example 473a was synthetized following the procedure for Example 1 using 4-(2-(2-tert-butylphenoxy)pyridin-3-yl)thiosemicarbazide (Example 1b) with chloroacetyl chloride.

Sources & evidence

ORD record: ord-63229f01359c43a3ab8225dfefc0f887
Source dataset: uspto-grants-2010_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07645778B2

Reaction notes

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