N-Methylisobutylamine → HCID 59128844, compound

HRID 1991390Notes

Reaction equation

[C:1]([C:5]1[N:6]=[C:7]([NH:12][C:13]2[C:14]([O:19][C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=3[C:26]([CH3:29])([CH3:28])[CH3:27])=[N:15][CH:16]=[CH:17][CH:18]=2)[S:8][C:9]=1[CH2:10]O)([CH3:4])([CH3:3])[CH3:2].[CH2:30]([NH:34][CH3:35])[CH:31]([CH3:33])[CH3:32]>>[C:1]([C:5]1[N:6]=[C:7]([NH:12][C:13]2[C:14]([O:19][C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=3[C:26]([CH3:29])([CH3:28])[CH3:27])=[N:15][CH:16]=[CH:17][CH:18]=2)[S:8][C:9]=1[CH2:10][N:34]([CH2:30][CH:31]([CH3:33])[CH3:32])[CH3:35])([CH3:4])([CH3:3])[CH3:2]

Participants

Reactant 2

HCID 12249N-Methylisobutylamine

HCID 59128769HCID 59128769, compound

Product 1

HCID 59128844HCID 59128844, compound

Procedure

Example A161 was prepared from (4-tert-butyl-2-(2-(2-tert-butylphenoxy)pyridin-3-ylamino)thiazol-5-yl)methanol (Example 252) and isobutyl methyl amine according to the procedure described for Example 272. (M+H)+=493.2.

Sources & evidence

ORD record: ord-9a484e7a550645febcf35db5ebb890a8
Source dataset: uspto-grants-2010_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07645778B2

Reaction notes

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