Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Allyl bromide | HCID 7841 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 6-Cyanopyridine-3-carboxylic acid | HCID 2761108 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 68690268 | HCID 68690268 | — |
Reaction Steps
4 mmol of 6-Cyanonicotinic acid were dissolved in THF. 1.5 eq. of Cs2CO3 were added he reaction stirred for 10 min. 1.5 eq allylbromide and a catalytic amount of KI were added he reaction heated to 100° C. for 4 h. The product was isolated via extraction from cetate/water.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07645776B2 |
|---|
| Source dataset | uspto-grants-2010_01 |
|---|
| ORD ID | ord-34c8c9b91ceb4c018aa6bccf3419d71f |
|---|
| Source note | uspto-grants-2010_01 |
|---|
