3,4-Diaminobenzonitrile → HCID 178509535, compound

HRID 1991414Notes

Reaction equation

HRID 1991414 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[NH2:10])[C:5]#[N:6].[N:11]([O-])=O.[Na+]>O.C(O)(=O)C.O>[NH:10]1[C:9]2[CH:8]=[CH:7][C:4]([C:5]#[N:6])=[CH:3][C:2]=2[N:1]=[N:11]1

Participants

5

Reactant 2

HCID 7372853,4-DiaminobenzonitrileHCID 23668193Sodium Nitrite

Product 1

HCID 178509535HCID 178509535, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 21899381Acetic acid--water (1/1)Solvent

Conditions

Temperature
0 °C

Procedure

10 mmol of 3,4-Diamino-benzonitrile were suspended in water/acetic acid (4:1) and cooled to 0° C. 1.05 eq of NaNO2 were dissolved in water and added inert 30 min. The reaction was stirred at room temperature overnight. The precipitate was filtered off, washed with ether and dried under vacuum. The intermediate was not further characterized.

Workup

  1. additionadded inert 30 min
  2. filtrationThe precipitate was filtered off
  3. washwashed with ether
  4. customdried under vacuum

Sources & evidence

ORD record
ord-80844e7fb20a450fa21781e8ff128fdd
Source dataset
uspto-grants-2010_01
Patent number
US07645776B2

Reaction notes

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