3-Cyclopentyl-2-(4-methanesulfonyl-phenyl)propionic acid → 3-Cyclopentyl-2-(4-methanesulfonyl-phenyl)-N-[4-methyl-5-(4-methylpiperazine-1-sulfonyl)-thiazol-2-yl]-propionamide

HRID 199189Notes

Reaction equation

HRID 199189 reaction equation
[CH3:21][c:22]1[n:23][c:24]([NH2:37])[s:25][c:26]1[S:27](=[O:28])(=[O:29])[N:30]1[CH2:31][CH2:32][N:33]([CH3:36])[CH2:34][CH2:35]1.[CH:1]1([CH2:6][CH:7]([C:8](=[O:9])[OH:10])[c:11]2[cH:12][cH:13][c:14]([S:17](=[O:18])(=[O:19])[CH3:20])[cH:15][cH:16]2)[CH2:2][CH2:3][CH2:4][CH2:5]1>>[CH:1]1([CH2:6][CH:7]([C:8](=[O:10])[NH:37][c:24]2[n:23][c:22]([CH3:21])[c:26]([S:27](=[O:28])(=[O:29])[N:30]3[CH2:31][CH2:32][N:33]([CH3:36])[CH2:34][CH2:35]3)[s:25]2)[c:11]2[cH:12][cH:13][c:14]([S:17](=[O:18])(=[O:19])[CH3:20])[cH:15][cH:16]2)[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

3

Reactant 2

HCID 120694893-Cyclopentyl-2-(4-methanesulfonyl-phenyl)propionic acidHCID 639461724-Methyl-5-(4-methyl-piperazine-1-sulfonyl)-thiazol-2-ylamine

Product 1

HCID 116925123-Cyclopentyl-2-(4-methanesulfonyl-phenyl)-N-[4-methyl-5-(4-methylpiperazine-1-sulfonyl)-thiazol-2-yl]-propionamide

Sources & evidence

ORD record
ord-ede293d6bbdc4ab797779c56ea2cca16
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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