4-(Trifluoromethyl)benzenesulfonyl chloride → HCID 58727984, compound

HRID 1992217Notes

Reaction equation

HRID 1992217 reaction equation
[CH3:1][C:2]([CH3:18])([C:6](=[O:17])[NH:7][S:8]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)(=[O:10])=[O:9])[C:3]([OH:5])=[O:4].[F:19][C:20]([F:32])([F:31])C1C=CC(S(Cl)(=O)=O)=CC=1>>[CH3:1][C:2]([CH3:18])([C:6](=[O:17])[NH:7][S:8]([C:11]1[CH:16]=[CH:15][C:14]([C:20]([F:32])([F:31])[F:19])=[CH:13][CH:12]=1)(=[O:10])=[O:9])[C:3]([OH:5])=[O:4]

Participants

3

Reactant 2

HCID 27773994-(Trifluoromethyl)benzenesulfonyl chlorideHCID 58728741HCID 58728741, compound

Product 1

HCID 58727984HCID 58727984, compound

Procedure

2,2-dimethyl-3-oxo-3-({[4-(trifluoromethyl)phenyl]sulfonyl}amino)propanoic acid was prepared in the same manner as 2,2-dimethyl-3-oxo-3-[(phenylsulfonyl)amino]propanoic acid starting from 4-(trifluoromethyl)benzenesulfonyl chloride.

Sources & evidence

ORD record
ord-b376943d603a46bc9e3d9cb5430073b5
Source dataset
uspto-grants-2010_01
Patent number
US07645771B2

Reaction notes

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