HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrimidine, 5-bromo-2-methoxy- → (5S)-5-({[4-[(2-Methoxypyrimidin-5-yl)ethynyl]-3,6-dihydropyridin-1(2H)-yl]sulfonyl}methyl)-5-methylimidazolidine-2,4-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrimidine, 5-bromo-2-methoxy- | HCID 139657 | — |
| Reactant | (5S)-5-{[(4-Ethynyl-3,6-dihydropyridin-1(2H)-yl)sulfonyl]methyl}-5-methylimidazolidine-2,4-dione | HCID 86642354 | — |
| Product | (5S)-5-({[4-[(2-Methoxypyrimidin-5-yl)ethynyl]-3,6-dihydropyridin-1(2H)-yl]sulfonyl}methyl)-5-methylimidazolidine-2,4-dione | HCID 11553220 | — |
Reaction Steps
The title compound was prepared from 5-bromo-2-methoxypyrimidine and (55)-5-{[(4-ethynyl-3,6-dihydropyridin-1(2H)-yl)sulfonyl]methyl}-5-methylimidazolidine-2,4-dione in the same way as described in Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07648992B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-58bc235cb3a144d08541106533568bde |
| Source note | uspto-grants-2010_01 |