HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloropyridine-5-boronic acid → HCID 86621934, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloropyridine-5-boronic acid | HCID 3845034 | — |
| Reactant | 1-{4-[5-(4-Isopropyl-piperazine-1-carbonyl)-1H-indole-2-carbonyl]-piperazin-1-yl}-2-methyl-propan-1-one | HCID 68533986 | — |
| Product | HCID 86621934 | HCID 86621934 | 43% |
Reaction Steps
The title compound was synthesized in analogy to example 5, after stirring for 6.5 days at 35° C., from 1-{4-[5-(4-isopropyl-piperazine-1-carbonyl)-1H-indole-2-carbonyl]-piperazin-1-yl}-2-methyl-propan-1-one (example 31) and 2-chloropyridine-5-boronic acid to afford the desired product as a light-brown foam (43%). MS (ISP): 565.4 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07648979B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-48068902e7554ae2a713a7b848d839c9 |
| Source note | uspto-grants-2010_01 |