HRID1992500

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID712909

n,n-dimethylpiperazine-1-carboxamide

C7H15N3O

结构：CC(C)(C)OC(=O)N1CCCN(C(=O)c2ccc3[nH]c(C(=O)O)cc3c2)CC1

HCID68535629

未命名化合物

PRODUCTS

生成物

结构：CN(C)C(=O)N1CCN(C(=O)c2cc3cc(C(=O)N4CCCN(C(=O)OC(C)(C)C)CC4)ccc3[nH]2)CC1

HCID68535601

未命名化合物

PROCEDURE

实验过程

The title compound was synthesized in analogy to example 47a), from 5-(4-tert-butoxycarbonyl-[1,4]diazepane-1-carbonyl)-1H-indole-2-carboxylic acid and piperazine-1-carboxylic acid dimethyl amide. White solid. MS (m/z): 527.3 (M+H)+.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-8b93f7b9ac634218bbfabff3beea3934
来源数据集: uspto-grants-2010_01
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07648979B2
来源说明: uspto-grants-2010_01

反应 SMILES

[C:1]([O:5][C:6]([N:8]1[CH2:14][CH2:13][CH2:12][N:11]([C:15]([C:17]2[CH:18]=[C:19]3[C:23](=[CH:24][CH:25]=2)[NH:22][C:21]([C:26]([OH:28])=O)=[CH:20]3)=[O:16])[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH3:29][N:30]([CH3:39])[C:31]([N:33]1[CH2:38][CH2:37][NH:36][CH2:35][CH2:34]1)=[O:32]>>[C:1]([O:5][C:6]([N:8]1[CH2:14][CH2:13][CH2:12][N:11]([C:15]([C:17]2[CH:18]=[C:19]3[C:23](=[CH:24][CH:25]=2)[NH:22][C:21]([C:26]([N:36]2[CH2:35][CH2:34][N:33]([C:31](=[O:32])[N:30]([CH3:29])[CH3:39])[CH2:38][CH2:37]2)=[O:28])=[CH:20]3)=[O:16])[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]