HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2,3-Dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)methanol → 2,3-Dihydro[1,4]dioxino[2,3-c]pyridine-7-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2,3-Dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)methanol | HCID 21873770 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2,3-Dihydro[1,4]dioxino[2,3-c]pyridine-7-carbaldehyde | HCID 21873668 | 61% |
Reaction Steps
A solution of (2,3-dihydro-[1,4]dioxino[2,3-c]pyridin-7-yl)-methanol (250 mg, 1.5 mmol) in dichloromethane (5 mL) was treated with manganese dioxide (650 mg, 7.5 mmol). After 3 days the mixture was filtered and evaporated affording a white solid (150 mg, 61%); MS (APCl+) m/z 166 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07648984B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-f256703b77f541818af53241d427f709 |
| Source note | uspto-grants-2010_01 |