HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1992551Generated: November 2, 2026
4-Hydroxybenzaldehyde → 4-[(3-Chlorophenyl)methoxy]benzaldehyde
https://huagongshe.com/reaction/1992551
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Hydroxybenzaldehyde | HCID 126 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-(Bromomethyl)-3-chlorobenzene | HCID 69838 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 4-[(3-Chlorophenyl)methoxy]benzaldehyde | HCID 735465 | — |
Reaction Steps
A 0.5 M solution of 1-bromomethyl-3-chloro-benzene (102.7 mg, 0.5 mmol) in acetone was added to a suspension of 4-hydroxy-benzaldehyde (67.2 mg, 0.55 mmol), K2CO3 (207.3 mg, 1.5 mmol) and KI (10.8 mg, 0.065 mmol) in acetone (7 ml). The reaction mixture was stirred for 2 hours at 70° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07649005B2 |
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| Source dataset | uspto-grants-2010_01 |
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| ORD ID | ord-f214ed48040344629613193a399af200 |
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| Source note | uspto-grants-2010_01 |
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