HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium bis(trimethylsilyl)amide → 348113-81-5
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium bis(trimethylsilyl)amide | HCID 2724254 | — |
| Reactant | (+/-)-2-Methyl 2-propionylsulfanyl-decanoic acid ethyl ester | HCID 11738193 | — |
| Product | 348113-81-5 | HCID 135411009 | 99.9% |
Reaction Steps
From 30 (469 mg, 1.55 mmol) and NaHMDS (3.87 mL, 3.87 mmol, 1.0 M in TH) following general procedure G was obtained 34 (397 mg, 70%). 1H NMR (300 MHz, CDCl3) (enol tautomer) δ 0.86 (t, J=6.8 Hz, 3H), 1.23 (s, 11H), 1.30-1.45 (m, 1H), 1.59 (s, 3H), 1.74 (s, 3H), 1.84-1.88 (m, 2H); 13C NMR (75 MHz, CDCl3) δ 7.48, 14.0, 22.6, 25.2, 25.9, 29.2, 29.4, 29.6, 31.8, 38.5, 58.2, 110.5, 180.9, 198.0. IR (NaCl) 2927, 1601 cm−1
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07649012B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-0ffd62f12eac4285b898f8ca7837859f |
| Source note | uspto-grants-2010_01 |