HCID 68539826, compound → HCID 68536371, compound

Participants

Reaction Steps

The oily mixture containing (65) was dissolved in ethanol (50 mL) and 10% Pd/C (200 mg) was added. The mixture was hydrogenated at room temperature using a hydrogen balloon overnight. Filtered through celite, the filtrate was concentrated to give 1.72 g of compound (66) (41% from the ketone) of the title compound as a colorless oil. 1H NMR (400 MHz, CDCl3): δ 0.89 (d, J=7.4 Hz, 3H), 0.91 (d, J=7.6 Hz, 3H), 1.21 (t, J=7.2 Hz, 3H), 1.70-1.80 (m, 1H), 2.10-2.20 (m, 2H), 2.20-2.30 (m, 1H), 2.44 (dd, J1=13.6 Hz, J2=7.4 Hz, 1H), 2.64 (dd, J1=13.7 Hz, J2=6.2 Hz, 1H), 3.79 (s, 3H), 4.04 (q, J=7.2 Hz, 2H), 6.70-6.80 (m, 3H), 7.15-7.20 (m, 1H).

Provenance & Evidence