Hydrochloric Acid → HCID 68538683, compound

Participants

Reaction Steps

6-(Methyloxy)-1-{[(methyloxy)methyl]oxy}-2-phenyl-3-propylnaphthalene (96) (0.65 g, 1.92 mmol) was treated with 4 M HCl in dioxane at room temperature to give 0.54 g (97%) of compound 97 as a light yellow oil. 1H NMR (400 MHz, CDCl3): δ 0.79 (t, J=7.3 Hz, 3H), 1.40-1.55 (m, 2H), 2.45 (t, J=7.7 Hz, 2H), 3.92 (s, 3H), 5.15 (s, 1H), 7.05-7.10 (m, 2H), 7.22 (s, 1H), 7.35 (d, J=7.3 Hz, 2H), 7.42-7.48 (m, 1H), 7.49-7.56 (m, 2H), 8.08 (d, J=9.5 Hz, 1H). LCMS (ESI): m/z 293 (M+H)+, m/z 291 (M−H)−.

Provenance & Evidence