HCID 86087083, compound → HCID 68537290, compound

Participants

Reaction Steps

N-Methyl-N-(methyloxy)-2-[3-(methyloxy)-1-propyn-1-yl]benzamide (143) (0.35 g, 1.50 mmol) was treated with benzylmagnesium chloride in THF to give 0.21 g (53%) of the title compound (144) as a light yellow oil. 1H NMR (400 MHz, CDCl3): δ 3.44 (s, 3H), 4.34 (s, 2H), 4.38 (s, 2H), 7.20-7.26 (m, 3H), 7.27-7.38 (m, 3H), 7.38-7.44 (m, 1H), 7.54 (d, J=7.7 Hz, 1H), 7.57 (d, J=7.7 Hz, 1H). LCMS (ESI): m/z 265 (M+H)+.

Provenance & Evidence