HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-Ethyl-3-methyl-3,7-dihydro-purine-2,6-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 7-Ethoxymethyl-1-ethyl-3-methylxanthine | HCID 19689194 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-Ethyl-3-methyl-3,7-dihydro-purine-2,6-dione | HCID 12905388 | — |
Reaction Steps
28.7 g (0.11 mol) of 7-ethoxymethyl-1-ethyl-3-methylxanthine were stirred at 60° C. for 60 hours in a solution of 200 ml of 5N hydrochloric acid and 200 ml of ethanol. The reaction mixture was concentrated to dryness and the residue which remained was crystallized in ethyl acetate/diisopropyl ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05728686 |
| Source dataset | uspto-grants-1998_03 |
| ORD ID | ord-1e4a1fe78dd64b49acf4eb3616e08f35 |
| Source note | uspto-grants-1998_03 |