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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1993292Generated: October 26, 2026

1-Bromohexadecane → 4-amino-1-[[(5S)-2-hexadecoxy-2-oxo-1,4,2$l^{5}-dioxaphosphinan-5-yl]methyl]pyrimidin-2-one

https://huagongshe.com/reaction/1993292

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-BromohexadecaneHCID 8213—
ReactantCyclic HPMPCHCID 122873—
Product4-amino-1-[[(5S)-2-hexadecoxy-2-oxo-1,4,2$l^{5}-dioxaphosphinan-5-yl]methyl]pyrimidin-2-oneHCID 48347255%

Reaction Steps

The title compound was prepared using the same procedure as described for Example 1 using 1-bromohexadecane and cyclic cidofovir.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07652001B2
Source datasetuspto-grants-2010_01
ORD IDord-1d3188b5b70e4a10971ea3677f6e1210
Source noteuspto-grants-2010_01