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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1993411Generated: October 26, 2026

5-Bromo-2-hydroxy-3-methoxybenzaldehyde → 6-[4-(5-Bromo-2-hydroxy-3-methoxy-benzyl)-piperazin-1-yl]-3H-pyrimidin-4-one

https://huagongshe.com/reaction/1993411

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-2-hydroxy-3-methoxybenzaldehydeHCID 262238—
Reactant6-piperazin-1-yl-3H-pyrimidin-4-oneHCID 136102540—
Product6-[4-(5-Bromo-2-hydroxy-3-methoxy-benzyl)-piperazin-1-yl]-3H-pyrimidin-4-oneHCID 136102576—

Reaction Steps

6-[4-(5-Bromo-2-hydroxy-3-methoxy-benzyl)-piperazin-1-yl]-3H-pyrimidin-4-one was prepared using Procedure A from 6-piperazin-1-yl-3H-pyrimidin-4-one (Intermediate 4) and 5-bromo-2-hydroxy-3-methoxybenzaldehyde. Mass spectrum (ES) MH+=395.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07652013B2
Source datasetuspto-grants-2010_01
ORD IDord-68c3bb565e94463fba366af0e09e4ea3
Source noteuspto-grants-2010_01