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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1993423Generated: October 26, 2026

5-Bromo-2-fluorobenzaldehyde → 6-[4-(5-Bromo-2-fluoro-benzyl)-piperazin-1-yl]-3H-pyrimidin-4-one

https://huagongshe.com/reaction/1993423

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-2-fluorobenzaldehydeHCID 736327—
Reactant6-piperazin-1-yl-3H-pyrimidin-4-oneHCID 136102540—
Product6-[4-(5-Bromo-2-fluoro-benzyl)-piperazin-1-yl]-3H-pyrimidin-4-oneHCID 136102550—

Reaction Steps

6-[4-(5-Bromo-2-fluoro-benzyl)-piperazin-1-yl]-3H-pyrimidin-4-one was prepared using Procedure A from 6-piperazin-1-yl-3H-pyrimidin-4-one (Intermediate 4) and 5-bromo-2-fluorobenzaldehyde. Mass spectrum (ES) MH+=367.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07652013B2
Source datasetuspto-grants-2010_01
ORD IDord-5ebf469a5d624332a93779549dee0c6f
Source noteuspto-grants-2010_01