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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1993428Generated: October 26, 2026

3,5-Dichlorosalicylaldehyde → 6-[4-(3,5-Dichloro-2-hydroxy-benzyl)-piperazin-1-yl]-3H-pyrimidin-4-one

https://huagongshe.com/reaction/1993428

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-DichlorosalicylaldehydeHCID 66660—
Reactant6-piperazin-1-yl-3H-pyrimidin-4-oneHCID 136102540—
Product6-[4-(3,5-Dichloro-2-hydroxy-benzyl)-piperazin-1-yl]-3H-pyrimidin-4-oneHCID 135879443—

Reaction Steps

6-[4-(3,5-Dichloro-2-hydroxy-benzyl)-piperazin-1-yl]-3H-pyrimidin-4-one was prepared using Procedure A from 6-piperazin-1-yl-3H-pyrimidin-4-one (Intermediate 4) and 3,5-dichlorosalicylaldehyde. Mass spectrum (ES) MH+=355.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07652013B2
Source datasetuspto-grants-2010_01
ORD IDord-2aa8ee5508bc4026bd98fee5b1f0580e
Source noteuspto-grants-2010_01