5-Nitrosalicylaldehyde → HCID 136102571, compound

HRID 1993433Notes

Reaction equation

HRID 1993433 reaction equation
[N:1]1([C:7]2[N:12]=[CH:11][NH:10][C:9](=[O:13])[CH:8]=2)[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.[OH:14][C:15]1[CH:22]=[CH:21][C:20]([N+:23]([O-:25])=[O:24])=[CH:19][C:16]=1[CH:17]=O>>[OH:14][C:15]1[CH:22]=[CH:21][C:20]([N+:23]([O-:25])=[O:24])=[CH:19][C:16]=1[CH2:17][N:4]1[CH2:5][CH2:6][N:1]([C:7]2[N:12]=[CH:11][NH:10][C:9](=[O:13])[CH:8]=2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 668085-NitrosalicylaldehydeHCID 1361025406-piperazin-1-yl-3H-pyrimidin-4-one2×

Product 1

HCID 136102571HCID 136102571, compound

Procedure

6-[4-(2-Hydroxy-5-nitro-benzyl)-piperazin-1-yl]-3H -pyrimidin-4-one was prepared using Procedure A from 6-piperazin-1-yl-3H-pyrimidin-4-one (Intermediate 4) and 2-hydroxy-5-nitrobenzaldehyde. Mass spectrum (ES) MH+=332.

Sources & evidence

ORD record
ord-112e78fef6c74d399af498ce2a9db314
Source dataset
uspto-grants-2010_01
Patent number
US07652013B2

Reaction notes

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