Benzaldehyde, 2-hydroxy-5-methyl- → HCID 136102554, compound

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Reaction Steps

6-[4-(2-Hydroxy-5-methyl-benzyl)-piperazin-1-yl]-3H -pyrimidin-4-one was prepared using Procedure B from 6-piperazin-1-yl-3H-pyrimidin-4-one (Intermediate 4) and 2-hydroxy-5-methylbenzaldehyde (available from Aldrich) (available from Aldrich). 1H NMR (400 MHz, CDCl3) δ 2.23 (s, 3H), 2.58-2.63 (m, 4H), 3.48-3.63 (m, 4H), 3.69 (s, 2H), 5.39 (s, 1H), 6.73-6.78 (m, 2H), 6.98-7.00 (m, 1H), 7.85 (s, 1H), 10.10 (br s, 1H), 12.75 (br s, 1H). Mass spectrum (ES) MH+=301.

Provenance & Evidence