HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Fluorosalicylaldehyde → HCID 136102582, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Fluorosalicylaldehyde | HCID 587788 | — |
| Reactant | 6-piperazin-1-yl-3H-pyrimidin-4-one | HCID 136102540 | — |
| Product | HCID 136102582 | HCID 136102582 | — |
Reaction Steps
6-[4-(3-Fluoro-2-hydroxy-benzyl)-piperazin-1-yl]-3H -pyrimidin-4-one was prepared using Procedure B from 6-piperazin-1-yl-3H-pyrimidin-4-one (Intermediate 4) and 3-fluorosalicylaldehyde (available from Aldrich). 1H NMR (400 MHz, CDCl3) δ 2.62-2.66 (m, 4H), 3.58-3.65 (m, 4H), 3.79 (s, 2H), 5.40 (s, 1H), 6.71-6.76 (m, 2H), 6.99-7.03 (m, 1H), 7.84 (s, 1H), 11.85 (br s, 1H). Mass spectrum (ES) MH+=305.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07652013B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-2157c6452b8a482e90911f19d95bf2dc |
| Source note | uspto-grants-2010_01 |