HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-difluoro-2-hydroxybenzaldehyde → HCID 136102567, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-difluoro-2-hydroxybenzaldehyde | HCID 2779374 | — |
| Reactant | 6-piperazin-1-yl-3H-pyrimidin-4-one | HCID 136102540 | — |
| Product | HCID 136102567 | HCID 136102567 | — |
Reaction Steps
6-[4-(3,5-Difluoro-2-hydroxy-benzyl)-piperazin-1-yl]-3H-pyrimidin-4-one was prepared using Procedure B from 6-piperazin-1-yl-3H-pyrimidin-4-one (Intermediate 4) and 3,5-difluorosalicylaldehyde (available from Aldrich). 1H NMR (400 MHz, DMSO-d6) δ 3.48-3.53 (m, 4H), 3.67 (s, 2H), 5.27 (s, 1H), 6.89-6.91 (m, 1H), 7.09-7.13 (m, 1H), 7.89 (s, 1H), 11.64 (br s, 1H). Mass spectrum (ES) MH+=323.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07652013B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-39796a77f4f14f8b84206dfb817784bd |
| Source note | uspto-grants-2010_01 |