HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Hydroxy-5-iodo-3-methoxybenzaldehyde → HCID 136102547, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Hydroxy-5-iodo-3-methoxybenzaldehyde | HCID 7020611 | — |
| Reactant | 6-piperazin-1-yl-3H-pyrimidin-4-one | HCID 136102540 | — |
| Product | HCID 136102547 | HCID 136102547 | — |
Reaction Steps
6-[4-(2-Hydroxy-5-iodo-3-methoxy-benzyl)-piperazin-1-yl]-3H-pyrimidin-4-one was prepared using Procedure B from 6-piperazin-1-yl-3H-pyrimidin-4-one (Intermediate 4) and 5-iodo-o-vanillin (available from Alfa Aesar, Ward Hill, Mass., USA). 1H NMR (400 MHz, CDCl3) δ 2.60-2.64 (m, 4H), 3.48-3.52 (m, 4H), 3.69 (s, 2H), 3.85 (s, 3H), 5.39 (s, 1H), 6.94-6.96 (m, 1H), 7.07 (s, 1H), 7.84 (s, 1H), 12.13 (br s, 1H). Mass spectrum (ES) MH+=443.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07652013B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-f0004ff8c689423abea3323ad6998194 |
| Source note | uspto-grants-2010_01 |